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Multiple Myeloma Staging

Stages of Plasma Cell Neoplasms KEY POINTS There are no standard staging systems for monoclonal gammopathy of undetermined significance (MGUS), macroglobulinemia, and plasmacytoma. After multiple myeloma has been diagnosed, tests are done to find out the amount of...

Multiple Myeloma Pathophysiology

Multiple myeloma is a cancer that develops in the bone marrow, the spongy tissue found in the center of most bones. The bone marrow produces red blood cells, which carry oxygen throughout the body; white blood cells, which form the body’s defenses (immune...

MRSA

The incidence of Methicillin-Resistant Staphylococcal Aureus (MRSA) continues to be a major health care concern in hospitals and the community. This infection encompasses a wide spectrum of severity, ranging from mild cellulitis to serious life-threatening necrotizing...

Measles Epidemiology

Pre-Vaccination era In the decade prior to the licensure of live measles vaccine in 1963, an average of 549,000 measles cases and 495 measles deaths were reported annually. However, almost every American was affected by measles during their lifetime; it is estimated...

Measles Diagnosis

Laboratory Diagnosis of Measles Laboratory confirmation is essential for all outbreaks and all sporadic measles cases. Detection of measles-specific IgM antibody and measles RNA by real-time reverse transcription polymerase chain reaction (RT-PCR) are the most common...